Oral Manifestations of Certain Systemic Disorders *

Lesions of the oral mucous membrane related to endocrine seasons such as menstruation, pregnancy, and the menopause, or to allergic states have usually been described as individual case reports. This paper deals with diagnoses and therapeutics in a group of patients with such lesions, seen in the New Haven Hospital. It presents clinical studies only, except in two instances in which biopsies were made and the results of the histologic examination are included. Bacteriologic investigations were omitted. Though the chief complaints in this group concerned oral lesions, efforts were made to demonstrate or exclude other pathologic conditions. Histories of these patients and their families were obtained in detail; physical examinations conformed with the routine used in this hospital; urine analyses and blood counts were done invariably, and gastric analyses, basal metabolism tests, etc., when indicated.